Dr. Joseph Buxbaum on use of IGF-1 to Treat Phelan McDermid Syndrome

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Dr. Joseph Buxbaum on use of IGF-1 to Treat Phelan McDermid Syndrome

In a small clinical trial with nine children who have Phelan-McDermid syndrome, three months of daily injections of insulin-like growth factor (IGF-1) improved social function and reduced repetitive behaviors. However, the powerful growth-stimulating hormone -- approved to treat short stature related to IGF deficiency in children -- may not be suitable for long-term use.

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